兔抗IL10RA(Phospho-Tyr496) 多克隆抗体

Background:

The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway.

Applications:

WB

Name of antibody:

IL10RA(Phospho-Tyr496)

Immunogen:

Peptide sequence around phosphorylation site of Tyrosine496 (K-G-Y(p)-L-K) derived from Human IL-10R alpha.

Full name:

interleukin 10 receptor, alpha

Synonyms：

CD210; IL10R; CD210a; CDW210A; HIL-10R; IL-10R1

SwissProt:

Q13651

WB Predicted band size:

63 kDa

WB Positive control:

Huvec cells lysates

WB Recommended dilution:

500-1000