兔抗HTR2A多克隆抗体

Background:

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

HTR2A

Immunogen:

Synthetic peptide of human HTR2A

Full name:

5-hydroxytryptamine receptor 2A

Synonyms:

HTR2; 5-HT2A

SwissProt:

P28223

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human colorectal cancer

IHC Recommend dilution:

50-100

WB Predicted band size:

53 kDa

WB Positive control:

Mouse brain tissue lysate

WB Recommended dilution:

500-2000