小鼠抗MYCN单克隆抗体

Background:

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Applications:

WB

Name of antibody:

MYCN

Immunogen:

Fusion protein of human MYCN

Full name:

MYCN proto-oncogene, bHLH transcription factor

Synonyms:

NMYC; ODED; MODED; N-myc; bHLHe37

SwissProt:

P04198

WB Predicted band size:

50 KD

WB Positive control:

HepG2 cell lysate

WB Recommended dilution:

200-1000