中文名称: 兔抗AD7C-NTP多克隆抗体
Background: |
The predicted AD7CNTP protein contains 375 amino acids and has a calculate molecular mass of about 42 kD. It is rich in serine and proline residues, has a 15-amino acid hydrophobic leader sequence, and has 7 putative membrane-spanning regions. AD7CNTP has several phosphorylation sites, a myristoylation site, and 2 serine/threonine kinase protein domains. Northern blot analysis detected 1.4- and 0.9-kb transcripts only in adult frontal and temporal lobe. In vitro studies demonstrated that overexpression of AD7CNTP in transfected neuronal cells promoted neuritic sprouting and cell death, the 2 principal neuroanatomic lesions correlated with dementia in AD. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
AD7C-NTP |
Immunogen: |
Synthetic peptide of human AD7C-NTP |
Full name: |
Neuronal thread protein AD7c-NTP |
Synonyms: |
AD7CNTP |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
41 kDa |
WB Positive control: |
Human fetal brain tissue |
WB Recommended dilution: |
200-1000 |