兔抗CDC25B(Phospho-Ser353)多克隆抗体

Background:

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2.

Applications:

WB

Name of antibody:

CDC25B(Phospho-Ser353)

Immunogen:

Peptide sequence around phosphorylation site of serine 353(R-R-S(p)-V-T) derived from Human CDC25B .

Full name:

cell division cycle 25B

Synonyms：

0

SwissProt:

P30305

WB Predicted band size:

65 kDa

WB Positive control:

COS7 cells lysates treated with Etoposide

WB Recommended dilution:

500-1000