中文名称:兔抗AURKC(Ab-202/175)多克隆抗体
Background: |
This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. |
Applications: |
WB |
Name of antibody: |
AURKC(Ab-202/175) |
Immunogen: |
Synthesized non-phosphopeptide derived from human AurB/C around the phosphorylation site of threonine 202/175 (C-G-T(p)-L-D). |
Full name: |
aurora kinase C |
Synonyms: |
AIE2; AIK3; ARK3; AurC; SPGF5; STK13; aurora-C |
SwissProt: |
Q9UQB9 |
WB Predicted band size: |
36 kDa |
WB Positive control: |
293,hela,hepg2 cell lysates |
WB Recommended dilution: |
500-3000 |