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Background: |
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. |
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Applications: |
WB |
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Name of antibody: |
THBD |
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Immunogen: |
Synthesized peptide derived from C-terminal of human THBD. |
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Full name: |
thrombomodulin |
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Synonyms： |
TM; THRM; AHUS6; BDCA3; CD141; THPH12 |
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SwissProt: |
P07204 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
K562 cells lysate |
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WB Recommended dilution: |
500-3000 |
