Background: |
The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene is highly similar to TBL1X gene in nucleotide sequence and protein sequence, but the TBL1X gene is located on chromosome X and this gene is on chromosome Y. This gene has three alternatively spliced transcript variants encoding the same protein. |
Applications: |
ELISA, IHC |
Name of antibody: |
TBL1Y |
Immunogen: |
Fusion protein of human TBL1Y |
Full name: |
transducin (beta)-like 1, Y-linked |
Synonyms: |
TBL1 |
SwissProt: |
Q9BQ87 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human lung cancer and Human thyroid cancer |
IHC Recommend dilution: |
25-100 |