Background: |
The protein encoded by this gene is a subunit of the cohesin complex, which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
STAG2 |
Immunogen: |
Fusion protein of human STAG2 |
Full name: |
stromal antigen 2 |
Synonyms: |
SA2; SA-2; SCC3B; bA517O1.1 |
SwissProt: |
Q8N3U4 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human esophagus cancer and human breast cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
141 kDa |
WB Positive control: |
MCF7 cells |
WB Recommended dilution: |
200-1000 |