Background: |
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. |
Applications: |
WB |
Name of antibody: |
SRY |
Immunogen: |
Synthesized peptide derived from internal of human SRY. |
Full name: |
sex determining region Y |
Synonyms: |
TDF; TDY; SRXX1; SRXY1 |
SwissProt: |
Q05066 |
WB Predicted band size: |
24 kDa |
WB Positive control: |
Hela cells lysate |
WB Recommended dilution: |
500-3000 |