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Background: |
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SPAG6 |
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Immunogen: |
Synthetic peptide of human SPAG6 |
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Full name: |
sperm associated antigen 6 |
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Synonyms： |
pf16; Repro-SA-1 |
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SwissProt: |
O75602 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and Human cervical cancer |
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IHC Recommend dilution: |
25-100 |
