Background: |
This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
GPBP1 |
Immunogen: |
Fusion protein of human GPBP1 |
Full name: |
GC-rich promoter binding protein 1 |
Synonyms: |
GPBP; SSH6; VASCULIN |
SwissProt: |
Q86WP2 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human tonsil |
IHC Recommend dilution: |
50-200 |