兔抗SIK1多克隆抗体

Background:

SIK1 (salt-inducible kinase 1), also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.

Applications:

ELISA, WB, IHC

Name of antibody:

SIK1

Immunogen:

Synthetic peptide of human SIK1

Full name:

salt-inducible kinase 1

Synonyms：

MSK; SIK; SNF1LK

SwissProt:

P57059

ELISA Recommended dilution:

1000-2000

IHC positive control:

Human cervical cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

85 kDa

WB Positive control:

HT-29 and hela cells, mouse liver tissue, A549 and Jurkat cells

WB Recommended dilution:

500-2000