兔抗F11R多克隆抗体

Background:

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

Applications:

ELISA, IHC

Name of antibody:

F11R

Immunogen:

Fusion protein of human F11R

Full name:

F11 receptor

Synonyms:

JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1

SwissProt:

Q9Y624

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human liver cancer

IHC Recommend dilution:

50-100