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中文名称： PARP11抗原（重组蛋白）
相关类别： 抗原
概 述
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Full name: |
poly (ADP-ribose) polymerase family, member 11 |
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Synonyms: |
ARTD11; MIB006; C12orf6 |
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Swissprot: |
Q9NR21 |
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Gene Accession: |
BC017569 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors; a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. |
