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021-54845833/15800441009
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Full name: |
neurotrophin 4 |
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Synonyms: |
NT4, NT5, NT-4, NT-5, NTF5, GLC10, GLC1O, NT-4/5 |
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Swissprot: |
P34130 |
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Gene Accession: |
BC012421 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. |
