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021-54845833/15800441009
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Background: |
This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CHRNA4 |
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Immunogen: |
Fusion protein of human CHRNA4 |
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Full name: |
cholinergic receptor, nicotinic, alpha 4 (neuronal) |
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Synonyms： |
EBN; BFNC; EBN1; NACHR; NACRA4; NACHRA4 |
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SwissProt: |
P43681 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human brain |
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IHC Recommend dilution: |
50-200 |
