中文名称: 小鼠抗PPARD单克隆抗体
英文名称: Anti-PPARD mouse monoclonal antibody
Background: |
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. |
Applications: |
WB |
Name of antibody: |
PPARD |
Immunogen: |
Fusion protein of human PPARD |
Full name: |
peroxisome proliferator activated receptor delta |
Synonyms: |
FAAR; NUC1; NUCI; NR1C2; NUCII; PPARB |
SwissProt: |
Q03181 |
WB Predicted band size: |
50 KD |
WB Positive control: |
NIH/3T3 cell lysate |
WB Recommended dilution: |
200-1000 |