兔抗KAT6A多克隆抗体

Background:

This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with an autosomal dominant form of cognitive disability. Chromosomal translocations of this gene are associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants.

Applications:

ELISA, IHC

Name of antibody:

KAT6A

Immunogen:

Synthetic peptide of human KAT6A

Full name:

lysine acetyltransferase 6A

Synonyms:

MOZ; MRD32; MYST3; MYST-3; ZNF220; RUNXBP2; ZC2HC6A

SwissProt:

Q92794

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer

IHC Recommend dilution:

25-100