兔抗IRS4多克隆抗体

Background:

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.

Applications:

ELISA, IHC

Name of antibody:

IRS4

Immunogen:

Synthetic peptide of human IRS4

Full name:

insulin receptor substrate 4

Synonyms:

IRS-4; PY160

SwissProt:

O14654

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human brain

IHC Recommend dilution:

50-100