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技术规格
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Background: |
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit |
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Applications: |
WB, IHC |
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Name of antibody: |
IRS1 (Phospho-Ser639) |
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Immunogen: |
Synthetic peptide of human IRS1 (Phospho-Ser639) |
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Full name: |
insulin receptor substrate 1 (Phospho-Ser639) |
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Synonyms： |
HIRS-1 |
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SwissProt: |
P35568 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
180 kDa |
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WB Positive control: |
293 cells untreated or treated with serum |
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WB Recommended dilution: |
500-1000 |
