中文名称:CBX8抗原(重组蛋白)
英文名称:CBX8 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to a region derived from 90-389 amino acids of human CBX8 |
技术规格
Full name: |
chromobox 8 |
Synonyms: |
PC3; RC1 |
Swissprot: |
Q9HC52 |
Gene Accession: |
BC009376 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |