兔抗IRF3(Phospho-Ser386) 多克隆抗体

Background:

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Applications:

WB

Name of antibody:

IRF3(Phospho-Ser386)

Immunogen:

Peptide sequence around phosphorylation site of Serine 386(A-S-S(p)-L-E) derived from Human IRF-3.

Full name:

interferon regulatory factor 3

Synonyms：

IRF3

SwissProt:

Q14653

WB Predicted band size:

47 kDa

WB Positive control:

293 cells and COLO cells lysates

WB Recommended dilution:

500-1000