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中文名称：CAPNS1抗原（重组蛋白）
英文名称：CAPNS1 Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
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Fusion protein corresponding to a region derived from 91-268 amino acids of human CAPNS1 |
技术规格
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Full name: |
calpain, small subunit 1 |
|
Synonyms: |
30K, CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4 |
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Swissprot: |
P04632 |
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Gene Accession: |
BC000592 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. |
