Background: |
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |
Applications: |
ELISA, WB |
Name of antibody: |
FZD4 |
Immunogen: |
Fusion protein of human FZD4 |
Full name: |
Frizzled family receptor 4 |
Synonyms: |
Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; CD344; FZD4S |
SwissProt: |
Q9ULV1 |
ELISA Recommended dilution: |
1000-2000 |
WB Predicted band size: |
60 kDa |
WB Positive control: |
Mouse heart tissue |
WB Recommended dilution: |
200-1000 |