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Background: |
After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB |
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Name of antibody: |
INSR(Phospho-Tyr1361) |
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Immunogen: |
Peptide sequence around phosphorylation site of Tyrosine 1361 (I-P-Y(p)-T-H) derived from Human IR. |
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Full name: |
insulin receptor |
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Synonyms： |
HHF5; CD220 |
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SwissProt: |
P06213 |
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WB Predicted band size: |
156 kDa |
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WB Positive control: |
293 cells lysates treated with Heatstock |
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WB Recommended dilution: |
500-1000 |
