购物车
帮助
021-54845833/15800441009
中文名称：CALD1抗原（重组蛋白）
英文名称：CALD1 Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
|
Fusion protein corresponding to a region derived from 26-207 amino acids of human CALD1 |
技术规格
|
Full name: |
caldesmon 1 |
|
Synonyms: |
CDM, HCAD, LCAD, H-CAD, L-CAD, NAG22 |
|
Swissprot: |
Q05682 |
|
Gene Accession: |
BC040354 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. |
