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抗 原： INS(C-peptide)
技术规格
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Background: |
After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
INS(C-peptide) |
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Immunogen: |
Synthetic peptide of human INS(C-peptide) |
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Full name: |
insulin |
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Synonyms: |
IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10 |
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SwissProt: |
P01308 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human tonsil and Human liver cancer |
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IHC Recommend dilution: |
25-50 |
