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  • CA9抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW9613
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:CA9抗原(重组蛋白)

英文名称:
CA9 Antigen (Recombinant Protein)

储      存:
冷冻(-20℃)

相关类别:抗原

概述

Fusion protein corresponding to a region derived from 113-414 amino acids of human CA9


技术规格

Full name:

carbonic anhydrase IX

Synonyms:

MN; CAIX

Swissprot:

Q16790

Gene Accession:

BC014950

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.