兔抗ILK(Phospho-Ser246) 多克隆抗体

Background:

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants.

Applications:

IHC

Name of antibody:

ILK(Phospho-Ser246)

Immunogen:

Peptide sequence around phosphorylation site of Serine 246(I-F-S(p)-H-P) derived from Human ILK.

Full name:

integrin-linked kinase

Synonyms：

P59; ILK-1; ILK-2; p59ILK; HEL-S-28

SwissProt:

Q13418

IHC positive control:

Human brain tissue

IHC Recommend dilution:

50-100