中文名称:ATF2抗原(重组蛋白)
英文名称:ATF2 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to C terminal 300 amino acids of human ATF2 |
技术规格
Full name: |
activating transcription factor 2 |
Synonyms: |
HB16; CREB2; TREB7; CRE-BP1 |
Swissprot: |
P15336 |
Gene Accession: |
BC130335 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. |