APP抗原（重组蛋白）

Full name:

amyloid beta (A4) precursor protein

Synonyms:

AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma

Swissprot:

P05067

Gene Accession:

BC004369

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease.