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021-54845833/15800441009
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Background: |
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
IKBIP |
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Immunogen: |
Fusion protein of human IKBIP |
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Full name: |
IKBKB interacting protein |
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Synonyms： |
IKIP |
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SwissProt: |
Q70UQ0 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer and Human lung cancer |
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IHC Recommend dilution: |
50-200 |
