储 存: 冷冻(-2℃)
Background: |
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. |
Applications: |
ELISA, IHC |
Name of antibody: |
ITGA5 |
Immunogen: |
Fusion protein of human ITGA5 |
Full name: |
integrin subunit alpha 5 |
Synonyms: |
FNRA; CD49e; VLA-5; VLA5A |
SwissProt: |
P08648 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human colorectal cancer |
IHC Recommend dilution: |
25-100 |