兔抗ACVR2A多克隆抗体

Background:

This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain.

Applications:

ELISA, WB, IHC

Name of antibody:

ACVR2A

Immunogen:

Synthetic peptide of human ACVR2A

Full name:

activin A receptor, type IIA

Synonyms：

ACVR2; ACTRII

SwissProt:

P27037

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human thyroid cancer and Human brain

IHC Recommend dilution:

25-100

WB Predicted band size:

58 kDa

WB Positive control:

293T cells, human fetal brain tissue and K562 cells, human fetal liver tissue and Hela cells

WB Recommended dilution:

500-2000