Background: |
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. |
Applications: |
ELISA, IHC |
Name of antibody: |
FUS |
Immunogen: |
Fusion protein of human FUS |
Full name: |
FUS RNA binding protein |
Synonyms: |
TLS; ALS6; ETM4; FUS1; POMP75; HNRNPP2 |
SwissProt: |
P35637 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
30-150 |