兔抗HTR1B多克隆抗体

Background:

The neurotransmitter serotonin (5-hydroxytryptamine; 5-HT) exerts a wide variety of physiologic functions through a multiplicity of receptors and may be involved in human neuropsychiatric disorders such as anxiety, depression, or migraine. These receptors consist of several main groups subdivided into several distinct subtypes on the basis of their pharmacologic characteristics, coupling to intracellular second messengers, and distribution within the nervous system (Zifa and Fillion, 1992 [PubMed 1359584]). The serotonergic receptors belong to the multigene family of receptors coupled to guanine nucleotide-binding proteins.

Applications:

ELISA, IHC

Name of antibody:

HTR1B

Immunogen:

Synthetic peptide of human HTR1B

Full name:

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

Synonyms：

S12; 5-HT1B; HTR1D2; HTR1DB; 5-HT1DB

SwissProt:

P28222

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human tonsil

IHC Recommend dilution:

25-100