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021-54845833/15800441009
别 名： HORMA domain containing 2; CT46.2
储 存： 冷冻（-20℃）
抗 原： HORMAD2
标 记 物： Unconjugate
Background:
Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation (By similarity).
Applications:
ELISA, IHC
Name of antibody:
HORMAD2
Immunogen:
Fusion protein of human HORMAD2
Full name:
HORMA domain containing 2
Synonyms:
CT46.2
SwissProt:
Q8N7B1
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human thyroid cancer and Human tonsil
IHC Recommend dilution:
50-200
技术规格
