兔抗HCN2多克隆抗体

Background:

Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain. Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). Produces a large instantaneous current. Activated by cAMP. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages.

Applications:

ELISA, IHC

Name of antibody:

HCN2

Immunogen:

Synthetic peptide of human HCN2

Full name:

hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Synonyms：

BCNG2, HAC-1, BCNG-2

SwissProt:

Q9UL51

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human breast cancer and Human ovarian cancer

IHC Recommend dilution:

50-200