中文名称:小鼠抗MSH2单克隆抗体
Background: |
This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
WB |
Name of antibody: |
MSH2 |
Immunogen: |
Fusion protein of human MSH2 |
Full name: |
mutS homolog 2 |
Synonyms: |
FCC1; COCA1; HNPCC; LCFS2; HNPCC1 |
SwissProt: |
P43246 |
WB Predicted band size: |
105 kDa |
WB Positive control: |
CEM, Jurkat, 293T, K562 and A431 cell lysates |
WB Recommended dilution: |
1000-5000 |