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中文名称：小鼠抗MRPL48单克隆抗体
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. |
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Applications: |
WB, IHC |
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Name of antibody: |
MRPL48 |
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Immunogen: |
Fusion protein of human MRPL48 |
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Full name: |
mitochondrial ribosomal protein L48 |
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Synonyms: |
L48MT; CGI-118; HSPC290; MRP-L48 |
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SwissProt: |
Q96GC5 |
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IHC positive control: |
Human breast tissue and Human colorectal cancer; Human lung cancer |
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IHC Recommend dilution: |
50-150 |
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WB Predicted band size: |
24 KD |
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WB Positive control: |
HepG2, Hela, Jurkat cell lysates |
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WB Recommended dilution: |
500-2000 |
