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021-54845833/15800441009
中文名称 : 小鼠抗MRPL11单克隆抗体
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Background: |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
MRPL11 |
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Immunogen: |
Fusion protein of human MRPL11 |
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Full name: |
mitochondrial ribosomal protein L11 (MRPL11), transcript variant 1 |
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Synonyms: |
CGI-113; L11MT; MRP-L11 |
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SwissProt: |
Q9Y3B7 |
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IHC positive control: |
carcinoma of human thyroid tissue and adenocarcinoma of human colon tissue; adenocarcinoma of human ovary tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
21 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
500-2000 |
