中文名称:小鼠抗MED28单克隆抗体
Background: |
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways. |
Applications: |
WB, IHC |
Name of antibody: |
MED28 |
Immunogen: |
Fusion protein of human MED28 |
Full name: |
mediator complex subunit 28 |
Synonyms: |
EG1; magicin; 1500003D12Rik |
SwissProt: |
Q9H204 |
IHC positive control: |
Human colon tissue and Human colorectal cancer |
IHC Recommend dilution: |
50-150 |
WB Predicted band size: |
20 KD |
WB Positive control: |
293T cell lysate |
WB Recommended dilution: |
500-2000 |