小鼠抗MAPK1/MAPK3单克隆抗体

Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Applications:

WB, IHC

Name of antibody:

MAPK1/MAPK3

Immunogen:

Fusion protein of human MAPK1/MAPK3

Full name:

mitogen-activated protein kinase 1/3

Synonyms:

ERK1, ERK2, ERK1/2

SwissProt:

P28482/P27361

IHC positive control:

Human liver cancer and Human gastric cancer; Human thyroid cancer and Human esophagus cancer

IHC Recommend dilution:

100-500

WB Predicted band size:

41/43 kDa

WB Positive control:

Human thyroid tissue, Human cerebella tissue, NIH/3T3 cell, 231 cell, Hela cell lysates

WB Recommended dilution:

1000-5000