小鼠抗MAP2K1/MAP2K2单克隆抗体

Background:

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Applications:

WB

Name of antibody:

MAP2K1/MAP2K2

Immunogen:

Fusion protein of human MAP2K1/MAP2K2

Full name:

mitogen-activated protein kinase kinase 1/2

Synonyms:

CFC3; MEK1; MKK1; MAPKK1; PRKMK1; CFC4; MEK2; MKK2; MAPKK2; PRKMK2

SwissProt:

Q02750/P36507

WB Predicted band size:

43 kDa

WB Positive control:

A549, MCF7 and Hela cell lysates

WB Recommended dilution:

500-2000