中文名称:小鼠抗LRRFIP1单克隆抗体
Background: |
Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. |
Applications: |
WB |
Name of antibody: |
LRRFIP1 |
Immunogen: |
Fusion protein of human LRRFIP1 |
Full name: |
LRR binding FLII interacting protein 1 |
Synonyms: |
GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1 |
SwissProt: |
Q32MZ4 |
WB Predicted band size: |
89 kDa |
WB Positive control: |
Raji, C2C12, MCF7 and Jurkat cell lysates |
WB Recommended dilution: |
1000-5000 |