中文名称:小鼠抗LDHB单克隆抗体
Background: |
This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. |
Applications: |
ELISA, WB |
Name of antibody: |
LDHB |
Immunogen: |
Fusion protein of human LDHB |
Full name: |
lactate dehydrogenase B |
Synonyms: |
LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281 |
SwissProt: |
P07195 |
WB Predicted band size: |
37 kDa |
WB Positive control: |
HepG2 whole cell lysate |
WB Recommended dilution: |
500-2000 |