小鼠抗LDHB单克隆抗体

Background:

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Applications:

ELISA, WB

Name of antibody:

LDHB

Immunogen:

Fusion protein of human LDHB

Full name:

lactate dehydrogenase B

Synonyms:

LDH-B; LDH-H; LDHBD; TRG-5; HEL-S-281

SwissProt:

P07195

WB Predicted band size:

37 kDa

WB Positive control:

HepG2 whole cell lysate

WB Recommended dilution:

500-2000