小鼠抗KRT16单克隆抗体

Background:

The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus.

Applications:

WB, IHC

Name of antibody:

KRT16

Immunogen:

Fusion protein of human KRT16

Full name:

keratin 16

Synonyms:

K16; PC1; CK16; K1CP; NEPPK; FNEPPK; KRT16A

SwissProt:

P08779

IHC positive control:

Human kidney cancer and Human ovarian cancer; Human thyroid cancer and Human endometrium tissue

IHC Recommend dilution:

500-2000

WB Predicted band size:

51 KD

WB Positive control:

HepG2 and Hela cell lysates

WB Recommended dilution:

500-2000