小鼠抗KRT8单克隆抗体

Background:

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Applications:

WB

Name of antibody:

KRT8

Immunogen:

Fusion protein of human KRT8

Full name:

keratin 8

Synonyms:

K8; KO; CK8; CK-8; CYK8; K2C8; CARD2

SwissProt:

P05787

WB Predicted band size:

54 kDa

WB Positive control:

Hela and A549 cell lysates

WB Recommended dilution:

10000-50000