小鼠抗KRT5单克隆抗体

Background:

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Applications:

WB

Name of antibody:

KRT5

Immunogen:

Fusion protein of human KRT5

Full name:

keratin 5

Synonyms:

K5; CK5; DDD; DDD1; EBS2; KRT5A

SwissProt:

P13647

WB Predicted band size:

62 kDa

WB Positive control:

C6, 3T3, A549, MCF7 and Hela cell lysates

WB Recommended dilution:

5000-10000